Walter White - 2017-05-18
Phenyl 2 propanone from acetone and benzene
Thanks! This is gonna help me a lot with my umm... school project
How dare you. Just because I'm not a girl that doesn't mean I don't have feelings. 😭
@Gavin Oleary yeah, i have stolen your dreams and your childhood
@Gavin Oleary please shut the fuck up
@Gavin Oleary nobody in this thread likes you, nobody in this thread agrees with you, and the fact you were EVER able to land a 6 figure job (if thats even tru lmfao) is further proof that there are a lot of people in society getting paid a shit ton to dress up in a suit and do a whole load of nothing
@little brunette wow
I accidentally make chloroacetone one day. I never really appreciated the term lachrymator until then.
So, I expect the warning regarding bromoacetone is well founded.
Does anyone runs this route especially from chloroacetone? In the end of this video chem player didnt sure about the product is p2p or not?! And a failure in yields,
(Nobody seemed to make a joke out of this yet, so here I am doing it)
Add some turpentine to it and you get a toon killer!
instructions unclear, ended up creating an entirely new class of psychoactive substances capable of curing any mental illness
Here's the problem with P2P in any decent quantity. It's worth more to violent terrorist types than it is to junkies, cooks or cops. You all have been warned don't get stupid with this stuff or surely some dude with no neck will be snooping around your house.
I almost felt asleep by studying but i opened my McMurry on page 1127
simply gona say that I fucking love you
Friedel-Crafts reaction?
Yes i think becouse it's catalyze by AlCl3
Sort of, a friedel crafts that works because of the keton/enolate tautomer, I think..
feds r watching
pure P2P has a phantastic smell!
This is simply the best way I think😂
yea 10% yield lmao
Does the bromium solution worm?
P2np reduction p2p tin cloride
Thanks, Walter White
Wtf chloro acetone seems 10x easier to make than bromoacetone you lost me 3mins in
Do all the elements on this physical dimensional plane have six sides to them. What about the five sided ones , the pentagonal spheres Who dwell in the unseen realm has anybody seen them ? 😂😂😂
@JOHN BLACK SUPER CHEMIST can this route done by catalysts of alch or should use albr? Once you said febr, can you describe the details?
Small yield :( If you don't have HCl you can use H2SO4, as same procedure with mix of ice to remove salts of AlCl3.
Why did you steal chem players video? Does he know you took it?
Aussie Chemist............Yeah I do not like it but chem player and nile red and them all know about it and they do not seem to care so who am I to try to stop it. He is associating their names with "walter white" which is a negative. And I guess that part hits a nerve too. What is funny is I am a little upset he did not steal any of my videos...........lmao. Is he to good to steal my videos. I can not stop laughing. Does he think he is better than me.........lol..............ANYWAYS...........have a good day
I'm personally happy he reposted, I've never heard of or visited the original posters video.
fancy josh...........wow you never heard of nile red or chemplayer. You should check out their channels. Chemplayer is on bitchute.com now. Chemplayer was the one who inspired me to post experiments. He has some VERY VERY VERY UNIQUE experiments.
@JBSC I'm extremely new with chemistry, just now looking into stuff like this. I'll have to check the others out thanks for the suggestion
@JBSC yeah anyone that's watched chemistry stuff on youtube knows who chemplayer is and nile red and cody and nerd rage and yourself im gona check out this bitchute.com now look for some new footage
come on guys how would one turn p2np into amphetamine
A much more easier way is a Grignard rxn between benzylmagnesium chloride and acetonitrile in diethyl ether. I think...
Gibt es noch andere deutsche Bürger die sich in diesen Ecken von Youtube rumtreiben?🤔
Cool
Is this the standard procedure, in other words, is it reasonably simple and safe/idiot-proof?
It's somewhat difficult and can be deadly. Safety precautions cannot be overstated or overdone. You can die during pretty much every step of this process for one reason or another.
@fancy josh Thanks for your comment. It seems that way just from looking at it...I think anyone considering doing any home-lab operation should learn all the OH&S stuff specifically concerning lab-work/chemicals. It would be a super idea to upload a video dedicated to this topic, "before you start, health & safety stuff..."
This reminds me of tcd but the chemistry depository was way less legal
Tcd?
When I added anhydrous AlCl3 to benzene,it slightly dissolved and its color had changed to yellow again,that meant it's not anhydrous anymore ,it separated 2 layers of benzene layer and chloroacetone+AlCl3 layer ,even heated,no more further reaction to become dark solution that is sign of P2P- production that it should be; Can somebody here explain about stop reacting like this?
Were you stirring the mixture?
Is this really p2p?
There are 2 methods that work fine: the rxn between Ac2O and PAA or dry distillation with lead acetate and phenylacetic acid.
@Nah! dude there are literally 20 more methods, just search on erowid
@БАТЬКА МАХНО nitroethane and benzaldehyde don"t work. Look at sciencemadness...
A grignard rxn with PhCH2XMg and acetaldehyde results in a Brown mixture due the acid alpha aromatic proton.
Chlorination of acetone is a messy reaction and the yields are less then 10%. There is another experimental YouTube video about that...
Pseudoephedrine or ephedrine from the farmacy is the wrong isomer after reduction of HI/RP at high temperatures
100mL Ac2O and PAA results in less then 11mL P2P. Both precursors are banned. Cut the yield in half after chiral resolution to obtain the actieve form. levo amphetamine results in a unpleasure nervous feeling.
Pb(IV) acetate works if you like to break your glassware.
Maybe a FC acylation Will do the job followed by bromination but AlCl3 have to be ultradry and the solvent used. To remove that carbonyl functions you have to perform a Wollf Kishner reduction under the fumehood due the effects of hydrazine.
The topic is how to make P2P.
I suppose you are smarter then me so which method works better according to your reply. Source please then I can react on that particular method.
I don't need Pfizer, I'm harder and sharper. I'm afraid you need it, literature result mostly in a failure.
The ONLY Way to learn new things is to try things out. Not only restricted to this reaction.
Good luck!
@Nah! You seem to be highly knowledgeable about this. I have some questions.
1. You say 100mL Ac2O and PAA have a max yield of 11mL, which let's assume is 100% theoretical yield. This reaction uses 25mL acetone, ~26.4g bromine and ~30mL benzene (50 is used but 30 is recovered unreacted with 10mL extra addition which is not counted) with a yield of ~3mL. Is it reasonable to assume this is mostly phenylacetone? What is the theoretical yield for this reaction?
2. The dry distillation of PAA and Pb acetate; what is the ideal temperature? What is the theoretical yield? Ratio of reactants?
I dount it
You could use chloroacetone instead which i make from acetone and chlorine from electrolysis of salt
@Antonio Lebron no i haven't tried it yet, but i will in the future
@Antonio Lebronbut i have made phenylacetone from other routes of synthesis
@Miguel Chacón I'm trying to find a way to get P2P and then amphetamine from legal and easily available ingredients (medicines, fertilizers, metals, etc.) and I've found only one suitable option - the Fidel-Crafts reaction, but the only missing ingredient is chloroacetone. Which route do you use? Do you use illegal and hard-to-find precursors?
@Antonio Lebron the phenylacetone can be made from benzaldehyde, search it up, there are other routes but they have hard-to-get-or-make precursors. You could try with impure chloroacetone and see what happens
@Miguel Chacón Mas facil pseudoE + aminacion reductora con LiHNa
Not making drugs.....names Walter white
the video is originally a ChemPlayer video who is no longer on youtube but can still be found on bitchute
Is it possible to exchange the brom with an other chemical?
@Flixer Studios addationally, chlorine gas is pretty easy to make as all you need is table salt and an electrolysis rig ;)
@Disaster Experiments also you can mix hydrocloric acid and bleach to produce it
@Flixer Studios Pretty confident iodine won`t work
@БАТЬКА МАХНО why's that
@Flixer Studios that is because both chlorine and bromine are more electronegative than iodine thus leaving more easily the acetone and making HX. Sure, you can use iodine, but chlorine or bromine would work faster. Now the thing with chlorine is that you have to gas it, so you lose some along the way, so bromine seems to be more convenient. I believe this is a shit method of making bmk anyways.
Long story short, a really low yielding prep that requires a WWI tear gas.
But its chemplayer :' )
I struggle to see how you're not a little bitch
jared garden The cost of smuggling those precursors across like 15 borders is probably why they only smuggle in the ephedrine.
Supposedly they get "smaller" Sudafed shipments from India by the steel shipping container.
Supposedly, Indian companies give workers "vacations" but the factory still runs full steam ahead, to fill "no questions asked" orders headed for Mexico, labelled "cement sacks" or other pain-in-the-ass-to-lift-and-inspect imports.
How TRUE it is idk, but I saw pictures of Indian ppl pooping in the street so I believe it.
jared garden try to sound smarter why don’t you.
First you stole that line from breaking bad
Second, yes all those elements can be gotten easily, but making any useful amounts would be a severe waste of time. Anyone with the least bit of chemistry knowledge would know that. I’m not a chemist at all, and I know that.
Also, 55% yields using an amalgam is really low. Typically one can see much higher.
Pseudoephedrine is not used by the cartels anymore, as it has been more controlled.
@Michael Smith Hi yes what do you mean when you say amalgam? Amalgam of what?
Slm
Slm amigo
anyone know how to make cathinones ?
Khat
By bromination (HBr/H2O2) of the corresponding substituted propiophenone which is made by electrochemical oxidation of 'xylene' which yields the corresponding substituted benzaldehyde.
Nah!
Huh lol
i was gonna make dmt but my parents robbed me, gonna kms
@I’m stupid, but haha you made me smile now haha add me on snap epicmiazga
why use bromoacetone when u can use chloroaceton, also if u use bromoacetone u shopuld not use AlCl3 but AlBr3 this is not how a friedel krafts alkylation works
@БАТЬКА МАХНО bromine a bitch to make, chlorine isnt.
Aside from the lachrymatory effects, why not use iodine? It's much easier to acquire and handle than bromine or chlorine.
Becaise brom is liquid instead of Cl which is a gas -> easier to handle in a small lab. Also, it doesnt matter if you use AlBr3 or AlCl3. Both of them work.
I have a Question, in the end of this video results are disappointing and chemplayer didnt sure about the p2p, is anybody run this experiment, and does this method works? Yealds are low but no problem who cares about benz3ne and acetone
That's a messy reaction and not selective either
What do you do with this synthesis? What are it's common uses I guess my question is. I should have stated besides making meth. I get that. Can you do anything else with it?
@Miguel Chacón Por cierto, para obtener MDMA tendrias que reducir MDP2P junto metilamina. Si lo haces con amoniaco o acetato de amonio se formara MDA. Como te he dicho en mi otro comentario, comorate el PIHKAL y le echas un ojo. Lo puedes encontrar por 20 pavos de segunda mano por internet
@Carlos Lancha ok si tienes razon quisas no ha estudiado mucha quimica y quisas mucho info que se, es de el internet pero la afetamina es lo mismo que speed (and amphetamine is made by reacting p2p with formamide to yield N-formylamphetamine which is then turned to amphetamine with HCl and NOT with ammonia
Ya yo se de el libro PIHKAL pero no lo a ha leído
@Miguel Chacón Exacto. Eso si es cierto.
Para comprender mejor la quimica tras la metsnfetamina podrias echarle un ojo a la sintesis que describe Gabriel Fernández en su canal. Te daras cuenta de que la meta es como el MDMA pero sin el metilendioxido que une sus posiciones 4 y 5
I know you can do anfetamines as well
You can achieve this synthesis with benzene/acetone/ manganese lll acetate under argon atmosphere. 90 min rxn are ok. Then you get for sure P2P.
@psycronizer How so?
@psycronizer I thought aromatic compounds were radical acceptors in manganese mediated coupling reactions (Cho, I.; Muchowski, J. Synthesis, 1991). This should mean a fairly decent yield. I'm not sure about benzene but furan reacts selectively at alpha position (~90%) so I would assume benzene would behave similarly. I'm new to organic chemistry and P2P but perhaps I'm missing something? Is there a ridiculously high requirement for the catalyst in the reaction? How much would be necessary for a given amount of mols of reactants? Can it not be reconstituted and reused following the reaction?
@psycronizer Sorry to bother you with so many questions but you must understand that the prospect of making P2P from common cheap chemical feedstocks in a direct substitution using only one catalyst is something of a big deal.
@psycronizer You're right. I just did some research, it's just not feasible to produce any decent amount of P2P using manganese(III)acetate. However I wanted to run something by you and see what you think. Apparently thallium(III)nitrate can oxidize olefinic compounds pretty quickly and efficiently. Namely, alpha-methylstyrene is oxythallated to phenyl-2-propanone dimethyl acetal which can then be hydrolyzed to yield P2P (~81%). Apparently the side product is thallium(I)nitrate. I was wondering if the thallium(I) salt can be reacted with nitric acid to reconstitute the thallium(III) salt but I couldn't find any info on this. If it can, then you only theoretically need a small amount of (admittedly expensive and toxic) thallium salt. Do you know if this is possible?
do you have a video that shows a Preparative isolation and purification of xanthohumol from hops (Humulus lupulus L.) by high-speed counter-current chromatography..
Title says "from acetetone and benzene", but uses like hundred other chemicals and catalysts.
@psycronizer ahaha so true... probably doesn't even know that conversion of p2p to methamphetamine is called the leukhart-wallach reaction
Velveteon I mean, there are many other routes as well
Only a meth dealer like Jessy would post a comment like this. Do you really expect chemistry is just putting two chemicals together? Come on dude...
Ive read this is like the worst method for p2p
It definitely is the worse, very old school
110mL Ac2O with PAA give a theoretical yield of 11,11mL P2P. The costs are way higher then the benefits. The reductive amination completly fails when there is moisture in the reaction mixture. One way is to make sodium triacethoxyborohydride which is very hygroscopic by the very exothermic preparation by adding exactly 12,6g NaBH4 + 20g CH3COOH. Add this to 8,2g to the imine. Thus far it failed probably due the fact that the air humidity was not close enough to zero.
The starting chemicals are 86g PAA (easy to prepare), 43g NaOAc without hydrates (!), ovendry moleculair sieve and 800mL Ac2O.
You need a to have a vacuum pump too. The average hobbychemist can never make it as this is done under a inert atmosphere for about 46h.
The second part is the reductive amination. You need a company or something to achieve it.
Lead(IV) acetate instead of Ac2O is in my opinion no cheaper alternative as you end up with a way hard to remove solid mixture and in the case of glass: the expensive glaswork even have to be broken.
There are other ways that work. I can tell you that as a chemist that succeeded to make the right dextro isomer you end up with a serieus depression if you use this powerful stuff. It give a huge euphoric intense rush and release so much dopamine that you are highly energetic and very euphoric.
So, even if you can make it my honest advice is think twice or you end up with an never going over feeling of depression. 😥
I bet you could take this P2P and synthesize pseudoephedrine hcl easier than buying Sudafed in the store any more.
He can react it with methlymine and get meth as better and easier way...
If it is really p2p
irony ...you mean...you can buy pseudo en every boots
lol
It should probably be noted that P2P is a Schedule II substance in the US and therefore it's illegal to perform this reaction without a DCD research license.
And?
I'm sure most, if not all, are familiar with the scheduling....if not, well, then they need to find out the hard way for going into it blindly. If one don't know the laws here then one certainly shouldn't be looking these over and definitely not attempting them .I don't endorse P2P or meth but chemplayers vids are informative
i dont think the goverment is after thousands of first degree chemistry students.
So why you watching it? Go watch barney videos then.
Really don't try this method if you don't have a fume hood or a gas mask. I did this an the bromoacetone burns in your eyes like sh*t.
Lmao
Maggie P - 2018-09-06
"...so don't get excited."
With that monotone robot voice talking at me, idk if I can stop the excitement.
Chemistry'sCuriosities Cannagorilla - 2019-05-17
Maggpie?
Fabri - 2020-10-02
Xd