SciShow - 2020-01-29
Fasthosts Techie Test competition is now closed! Learn more about Fasthosts here: https://www.fasthosts.co.uk/scishow Our immune systems are generally pretty great, but sometimes they can turn on us. And for some reason, these autoimmune conditions mostly affect women. Hosted by: Hank Green SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at http://www.scishowtangents.org ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Kevin Carpentier, Eric Jensen, Matt Curls, Sam Buck, Christopher R Boucher, Avi Yashchin, Adam Brainard, Greg, Alex Hackman, Sam Lutfi, D.A. Noe, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, Charles Southerland, Patrick D. Ashmore, charles george, Kevin Bealer, Chris Peters, Ron Kakar ---------- Looking for SciShow elsewhere on the internet? Facebook: http://www.facebook.com/scishow Twitter: http://www.twitter.com/scishow Tumblr: http://scishow.tumblr.com Instagram: http://instagram.com/thescishow ---------- Sources: https://www.statista.com/statistics/418328/diagnosed-autoimmune-conditions-prevalence-in-selected-countries/ https://rarediseases.org/rare-diseases/stiff-person-syndrome/ https://www.medicalnewstoday.com/articles/246960.php#1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114837/ http://pubs.sciepub.com/ijcd/3/4/8/ https://medlineplus.gov/autoimmunediseases.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630965/ https://www.ncbi.nlm.nih.gov/books/NBK459262/ https://labblog.uofmhealth.org/lab-report/why-women-get-autoimmune-diseases-far-more-often-than-men https://healthjournalism.org/blog/2018/11/women-more-often-misdiagnosed-because-of-gaps-in-trust-and-knowledge/ https://www.sciencedirect.com/science/article/pii/S0091302214000466 https://transcare.ucsf.edu/sites/transcare.ucsf.edu/files/Transgender-PGACG-6-17-16.pdf https://www.sciencedirect.com/science/article/pii/S2050116117300454 https://www.sciencedirect.com/science/article/abs/pii/S1568997209001761?via%3Dihub https://www.thelancet.com/pdfs/journals/landia/PIIS2213-8587(15)00032-7.pdf https://www.sciencedirect.com/topics/immunology-and-microbiology/variolation https://www.nlm.nih.gov/exhibition/smallpox/sp_variolation.html https://profiles.nlm.nih.gov/spotlight/mm/feature/specificity https://absoluteantibody.com/antibody-resources/antibody-overview/a-brief-history-of-antibodies/ https://www.ncbi.nlm.nih.gov/pubmed/27131478 http://centennial.rucares.org/index.php?page=Autoimmune_Diseases https://www.nature.com/articles/ni0401_279 https://www.ncbi.nlm.nih.gov/pubmed/19883799 https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2141.2007.06531.x https://med.stanford.edu/news/all-news/2013/12/in-men-high-testosterone-can-mean-weakened-immune-response-study-finds.html https://www.ncbi.nlm.nih.gov/books/NBK26884/ https://www.hindawi.com/journals/scientifica/2012/215308/ https://www.sciencedirect.com/science/article/abs/pii/S0008874915000313#f0005 https://www.nature.com/articles/s41467-018-04408-0#Sec12 https://www.ncbi.nlm.nih.gov/pubmed/8570620/ https://www.ncbi.nlm.nih.gov/pubmed/19828378/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894651/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712643/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097198/ https://www.ncbi.nlm.nih.gov/pubmed/22178198 https://medicalxpress.com/news/2019-08-chromosome-gene-women-prone-autoimmune.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640911/ https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017873 https://www.nature.com/articles/5201614 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329817/ https://omrf.org/2016/06/13/does-x-mark-the-spot-a-new-clue-why-autoimmune-diseases-target-women/ https://genome.cshlp.org/content/23/9/1474.short https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0591-7 https://www.pnas.org/content/114/13/3491 https://www.pnas.org/content/114/15/3787 https://www.sciencedaily.com/releases/2019/06/190612084355.htm https://www.cell.com/trends/genetics/pdf/S0168-9525(19)30079-4.pdf
My thyroid: * exists *
My immune system: idk about that fam, seems pretty sketchy
My mom had to take thyroid blockers while she was heavily pregnant with me, for a highly overacting thyroid, she had a goiter removed soon after my birth. So my immune system decided to underdevelop my thyroid (undetected) and later on added Hashimoto to the mix as a way of thoroughly getting rid of it xD only when that happened I was examined at length. Vy then the stigma of lazy, unsporty potatoe had already manifested...
Same
I have hashimotos too... :P
If almost completely fixed itself though with the Paleo diet
Same…hyperthyroidism 😂
@bluetoes591 my dad got Graves’ disease…weird!
Summary of this lesson:
X gon give it to ya
❤ that! Totally put a smile on my face!
'Don't wait to get it on your own, X gonna deliver to ya.'
Pimp my autoimmune system!
Nice
🙌🤣😭 thanks
He did it! First we gonna rock, then we gone roll
And people tell you "But you don't LOOK sick...."
@Ashley M. I too have Aspergers and if you ever wanna talk, I'm here for you, girl. ;3
Or, you're too young!! Wth? People can be born with it!!!
@M E : Brilliant!!
@M E 🤣🤣🤣🤣🤣 I love that one!
@Jeff Miller best way to respond to that is to ask them questions that reveal their ignorance like:
Oh..what is Autism? And what is it supposed to look like? Ect.
Women’s immune systems: The time has come. Execute Order 66.
Their T-Cells: It will be done, my lord.
I AM THE SENATE!!
🤣
😉😉 I saw what you did there . . . Awesome!!
@Death Yoh I was talking to Eli, she deleted her comment
@ᚠᛁᛗᛒᚢᛚ ᚦᚢᛚᚢᚱ I know.
My skin * exists *
My immune system: “ya, gonna have to get rid of that”
Me: 😢
😂 exactly how mine acts too
As an eczema sufferer, I feel this. See what I did there?
When people talk about losing their skin, all I think is "It rubs the lotion on its skin"
P.S. Don't take that the wrong way, I have dated a girl with psoriasis before. Your skin isn't really going to be a deal breaker for most guys or girls. Unless they want to wear your skin or something creepy like that.
Scleroderma?
same
My bone marrow: helps the immune system
My immune system: seems sketchy. Let's take it out.
Damn my immune system self sabotaging as much as I am
Isabelle Harvey 🤣😂
The betrayal!
Marie S. definitely on my top 10 greatest anime betrayals.
IT'S A COUP!!!!
Ngl this is probably the most validating video I've ever watched
Yes, I agree
Age 8: Chronic eczema
Age 14: Chronic croup becomes asthma
Age 16: Onset of chronic migraines
Age 17: Graves' disease (hyperthyroidtoxicosis)
Age 19: Lactose, gluten, soy allergies
Age 21: Fibromyalgia, connected to underlying genetic collagen problem
Age 22: Irritable bowel disease
Age 26: Rapid severe onset of rheumatoid arthritis
My ambitious aspirations: am I a joke to you
@A Depressed Woodchuck Less sick than her real body, let's hope
Hey a lot of these are common co-morbidities to a condition called Mast Cell Activation Syndrome, which causes pseudoallergic reactions to various things. The fact that you have multiple allergies is also pretty suspect. I also want to note that it can masquerade as IBS, and migraines too for that matter. I suggest you see an immunologist and ask to receive an 11-beta prostaglandin F2 alpha test to see if you have MCAS. A lot of doctors don't know about MCAS because it was only recently discovered by the scientific community, and some of the ones that know about it might have misconceptions about testing. The 11-beta prostaglandin F2 alpha test is the best one to get, since the other tests have high rates of false negatives. Here's some info on MCAS symptoms and the like:
https://www.brighamandwomens.org/medicine/gastroenterology-hepatology-and-endoscopy/advances-newsletters/reducing-gastrointestinal-symptoms-using-mast-cell-disorder-identification-and-treatment
This is me!!
22 poopy
Your immune system didn't get the memo to not bite the hand that feeds them, huh?
I guess nature figured that childbirth, periods and menopause aren't enough to deal with so we clearly needed an extra vulnerability... 🙄
Yay!!
Evolutionarily, autoimmune diseases were much less of a problem than infections, so having a more reactive immune system was a bonus not a vulnerability.
Nature sucks.
It should be noted they specified this bias exists in transgender women though, who don’t have to deal with those things.
Men also have extra vulnerability! We have way stronger immune systems in general (even hyperactive as it's evident with autoimmune disease). But we also suffer less cardiovascular diseases and are less likely to develop Psychosis and Schizophrenia, substance abuse and so much more.
My colon: * exists *
Immune system: Beware the ides of March
Immune system: Every day is the ides of March btw
Two years ago I had Graves’ disease, immune system just starts attacking your thyroid, there was no clear trigger except that I had lost a close friend so you might say “stress” (though one common trigger is pregnancy so clearly that’s a not always protective for every autoimmune disease). The weird thing about Graves though is often when you treat the resulting overactive thyroid, sometimes the autoimmune just....stops.
That’s what happened to me and I have to say after that whole year I’m convinced they haven’t the slightest idea what’s going on. Just told me to “avoid stress”. Sure mate, I’ll be sure no one I love ever dies again.
My autoimmune reaction stopped too, but five years later it came back and just wouldn't stop again. Got my thyroid out two years ago, best decision for me.
@M water_moon "so much of the video"? It was like 2 minutes of a 15 minute video. I think it's good he included as much theories as he did. With over 80 different autoimmune diseases, there are going to be different causes. That some of them are triggered by pregnancy or have no relation to pregnancy, doesn't mean a lot of the others can be triggered by a lack of pregnancy.
Agreed! When my T1 diabetes came on fast onset at age 19 we knew it had a genetic component, as my mother is T1, but not what triggered it, since I had made it so many years without it. But I had just gone through a terrible breakup with a boyfriend who was very abusive and I always wonder if the stress and trauma set off my immune response. Of course no way to know, I could have simply caught a cold or virus I never even knew I had. But a lot of people suspect stress causes autoimmune reactions.
Not sold on the pregnancy theory either. Rates of autoimmune disease have risen in men as well as women, even if the raw numbers still favor women. Childbirth rates tend to drop with increased industrialization, economic growth, and adoption of more "western" lifestyle, and autoimmune conditions (along with allergies, another dysfunction of the immune system) increase under the same conditions. I think it's a case of correlation rather than causation. And globally, the number of endocrine- and immune-disrupting substances that have been put into the water, air, and soil have exploded since the mid 20th century, and many of these pollutants (such as PCBs for one example) do not degrade or diminish much over time but rather cycle through the food chain and environment repeatedly.
I think the pregnancy theory may also be about how having pregnancies earlier and more often in life may be protective, since the general trend is that people are having less children and later in life, but I absolutely agree this could easily just be correlation and not causation.
Gluten and my thyroid: exist
My immune system: STOP! YOU'VE VIOLATED THE LAW!
SAME
I'm a Twin (identical) and I have Graves Disease (a stress induced autoimmune disease) but my sister hasn't developed it.
@Lynn Rolaf "That means SAME DNA."
Nope. Not completely.
Even in your body cells of the same kind might have some differences in their DNA due to mutations that randomly occur and sometimes add up over several cell divisions.
NERD WARNING: Since you’re both girls, that could be related to X-inactivation. Identical twins can have very different patterns. Actually, there was a case where two twins carried a fatal X-linked disease, but only one was affected.
@Lynn Rolaf yes I know that but one of my passions is an exact cause...I was diagnosed with graves disease when I was nine just like you i feel like its stress
I know what a twin is..I was just saying after multiple radioactive iodine therapies and its still there it sucks
I'm an identical twin. I have MS. My twin has a 33% chance of being diagnosed with MS in her life. I hope she doesn't get it. But, if she does I'll be there to help her through it.
Very interesting information. I have an a.i. named ankylosing spondylitis. Along with osteoarthritis. Big , gentle, hugs for all autoimmune sufferers/warriors.
My dad just got diagnosed with this. His doctor said his kids likely have it, too. My sister and I have both had something ai since our mid 20s. The doctors never figured out what ours is. Just that it's something autoimmune. Maybe we have AS, too. Maybe the drs didn't look for it in us because we're female. It's pretty obvious on my x-ray, though. My dr told me my x-ray looked like that of someone 25 years older than I was at the time. It hasn't been fun. Yet I don't qualify for disability because I gave up on drs before getting a diagnosis.
@VirgLibrSagLove I was undiagnosed for a long time yet had tell tale signs. It took an incident that caused severe debilitating pain and a new family doctor to put all the pieces together. Now I'm able to manage well enough to work and function thi not " normal" but works for me.
@Michael Puffenbarger I'm really glad you're able to function and are feeling at least better now. My dad seems to be doing better with his new medication, too. With no health insurance and limited funds I've been self treating for many years. I have to admit, self treatment hasn't been effective enough for me, though. Some sort of steroid and massive pain medicine would be nice, I think. Thank you for caring and responding, by the way.
@VirgLibrSagLove your welcome. There are many facebook groups focused on AS that are helpful and supportive. A few focus on diet as a control, although I find its helpful just not a cure all. The best thing to do is research AS. Spondylitis.org arthritis.org https://www.facebook.com/groups/1497953407147354/?ref=share. This is one group I'm in. Good place to ask questions but no one is a doctor so cant give medical advice but it's an outstanding group.
Hello, Fellow AS badass. Hope you're doing well.
It has been suggested that there is a relationship between autoimmune disorders, stress, and trauma. Trauma experiences in children disproportionately affect girls. I know 3 women with autoimmune disorders, two of which have at least two children, and one who has never been pregnant. However, they all share a history of high stress and trauma. It would be interesting to see studies on this possible connection.
Me : i don't want to live anymore
My immune system : your wish is my command
Id love to see a deep dive on this happen, unfortunately our current medical structure is too narrow minded and focused on surface level symptom treatment to really see the whole picture of any medical issue.
@Matt Dupuis i know you commented the "this isnt the 1920s, we dont hate women anymore" thing 10 months ago but that is such a horrendously shitty take that i had to comment my awe. dont you have to be stupid somewhere else, or not till 4?
@saouer your comment is unintelligble, can you rephrase it?
Trauma does not disproportionally affect girls. People just ignore trauma when it happens to boys.
Thank you for addressing autoimmune diseases. I have Ulcerative colitis (apparently Hank does too?! I just found this out!) that really threw a wrench in my life my senior year of high school. It’s still an adjustment and I still grieve my old, healthy self. I also have endometriosis, hEDS and potentially Dysautonomia too.
I’m adopted so we really don’t know/have any familial medical history which adds even more complexity to my situation.
Invisible illnesses suck! I’m not any less sick just because I “look” normal. 🦓
U.C. , like crohn's isn't exactly autoimmune
Sumaiya Haque it isn’t 100% understood. Some research suggests it isn’t autoimmune but not enough to know for sure. For now, my care team (at Stanford Hospital) still considers it autoimmune.
Huh guess UC is way more common than i thought... Thats comforting
this condition can affect you if you have got ankylosing spondylitis which i have but i havent had UC
The sheer amount of information in this video, and my ability to actually understand it all despite doing very little with science, has awakened me to the true purpose of scishow. Thank you for slowly molding this world
I'm a Dude with Agammaglobulinemia
put it simply, My Immune Cells Have No Weapons so They have to Kamikaze Themselves to Enemies
That’s not an autoimmune disease, it’s an immunodeficiency. The exact opposite.
@vallauritz311 then why the hell am I always in room with one?
Gary Hamad probably because both concern immunology experts...?
that's probably really bad n i don't wanna downplay anything but that also sounds baller as hell
It was very entertaining to, as a Swede, hear Hank pronounce Sjögren xD
I have Hashimoto's and a fibro variant: I don't have the overall pain, but, boy, do I have tender points!
@Momera- Every tree months. I had the goiter aspirated like 15 years ago. It might be age too, I'll be 74 in a couple of days. My doctor tried switching me to "natural" (ground up monkey thyroids), some time ago.Didn't do any better, cost a WHOLE LOT more, and I hated having monkey die on my account.
@Christel Headington Oh wow that sucks :( I'm sorry the medications don't work for you, hypothyroidism/being cold all the time is awful
@Christel Headington Can we get a free pass to punch them when Dr's and nurses tell us to "calm down"??
I've had Hashimoto's for 25 years and was diagnosed with fibro 6 months ago, but likely had it a while longer. I have a stack of other health issues tacked on, including Reynauds syndrome which causes those lovely blue colours in toes, nose, fingers etc.
Fighting invisible monsters...
@snakebte1 well i was diagnosed with Hashimoto's at 13 so...
"There you have it, or there you don't have it." Love it. Lol. Such is this immensely complicated field of study. I do hope we can obtain some concrete answers soon. Thanks for the informative video!
This was one of the most interesting episodes in recent memory!
“We’re just sitting on the couch, shoving our faces full of Doritos or whatever”... but THAT’S EXACTLY WHAT IM DOING RIGHT NOW, HANK HOW DID YOU KNOW??
I was just thinking of if this phenomenon was true for trans women as well and then it got to that part of the video. This is actually pretty crazy to learn tbh.
I’ve been waiting for something like this. My mother has three autoimmune diseases and it’s drastically affected her life, to the point where she can’t even go out in the sun for more than 30 minutes at a time.
My mother isn't well suited to sunlight either but I think it is just because she is really pale.
Gareth Baus it’s not so much that my mother’s pale (even though she is). One of the three diseases is lupus and going out in the sun causes it to flare up horribly.
@AbiGrace I was talking about my mother with the being pale part, I figured you were talking about the effects of sunlight on the immune system.
Shout out to Crohn’s disease! Always there, and always cramping our style!
@HeyHay I also have ostomy for 3 months now!
This comment was funny. Psoriasis psoriatic arthritis here.
Crohns, colitis, sacroiliitis, psoriasis and vaskulitis here ;)
Accumulated over 23 years ( half my life)....
It's been a year, but I'll pile on. Thanks for making this video, Hank and SciShow! It's good to know that people are actually studying this closely, because Crohn's really sucks sometimes. Also, I'm a guy so I guess I'm a rarity? Not sure if it the sex difference applies to Crohn's.
I have Crohn and ironically docs discovered that my mother has Colitis after I was diagnosed. Sadly I also suffer from arthritis. The stomach pain is annoying and idk if I should be happy or not that it increased my pain tolerance cuz 3 medicine switch further I had to get surgery.
My connective tissue: exists
My thyroid: exists
My immune system: screeching in the background
My nerves: exist and do useful things
My immune system: DIEEE!!!
Hey, me too!
Hank, as a Biochemist who studied immunology, I appreciate the amount of study you had to do for this episode.
From the boatload of women with Hashimoto's disease: thank you for making this episode. Nobody knows why we get sick, and it sucks! More science, pls!
If the pregnancy hypothesis is true, then having more pregnancies would technically work... you’d just end up with a lot of kids.
Not if you're transgender, kinda hard to be pregnant without a uterus. Believe me I've tried
When I was diagnosed back around 2007, one of the things a lot of women in the spoonnie community said was their symptoms or conditions (in this case fibromyalgia and RA) were less intense/went into "remission" during pregnancy. It'd be interesting to see the research around their experiential observations.
So your body literally self destructs
Wtf
sighs in crohns disease at least theres still someone looking for answers
Explaining my autoimmune condition is always fun, because I get to watch people's faces when I say the words 'Hemophagocytic Lymphohistiocytosis' and then summarize it as 'my white blood cells went rogue and tried to kill me'. Like somehow the big red self-destruct button got pushed.
Aww that sucks. Mine luckily had a nickname (morphea) and is pretty simple (localized schleroderma)
Same. I have Hashimoto's Disease, and I explain it as my immune system attacks my thyroid gland, which regulates a lot of different hormones in the body. This means that, whenever I get a virus that looks similar to thyroid tissue, such as influenza, my immune system goes into overdrive and attacks my thyroid gland, which causes me to crave carbohydrates because my pancreas doesn't get the signal to produce insulin so that my cells can absorb the carbs to make all the energy they need.
@rdizzy1 same with me and my mom we have "Lupus" but have so many other symptoms that aren't related to just the integumentary system, like some stuff with the skeletal system.
When I was like 12 I had junior idiopathic arthritis and when anyone asked I would just say my immune system is really stupid and tried to attack my joints which was why I couldn’t make my hands flat lol
MysMiranda M. Me too!!
Thank you for bringing light to medical biases! This was a very interesting episode. Especially since I have another understudied disease more common in women (though not auto-immune).
My irises: exist
My immune system: "ain't enough room in this body for the both of us pal"
Yay, uveitis! Love the flares when the irises go all clover shaped!
Jesus Chicken Christ I just googled that and I have to say it's equal parts terrifying and fascinating!
I am surprised by the direction the comments went to. I am a 56 year old Male, born and raised male, diagnosed 3 years ago with an autoimmune disease. I am one of the lucky 25%. I been told that I am one in a million. Been led to believe that my DNA has been reprogrammed trigged by the ebsteen barr virus. Spent most of my life active and healthy until 8 years ago, health issues slowly came up as the disease morphed into what I have today. It is very difficult to have any doctor look at your test results and say you have a disorder if they have never seen it before, guys have always been told to "walk it off", and I tried. This is for real, it was trying to kill me. I was ill for years not knowing what was causing my health to deteriorate when a young female ER nurse pointed out what it could be. Treatment started soon after. I will be on immunosuppressants for for the rest of my life. I was hoping the comment section would be a little more constructive.
Well, you could be like my best friend who is a white woman with a black man's autoimmune disease. (Statistically speaking, more than 99% of all cases are in males, with about 70% in black males, so she's a medical enigma.) If someone can figure that one out, I'd love to hear it!
Aww... was that your first time being dismissed and ignored by 'specialist' making you feel like you're losing your mind because you know you're really in a bad shape but they can't see anything wrong with you? Bless xx
I wonder what you expected.
If for you explaing your own autoimune problem is not productive why did you comment that too?
If you want the comment section to be more productive why don't help it be more productive.
Constructive how? None of us know what causes all this crud, I wish we did. This stuff runs in my Dad's side of the family, he's got some minor issues, my sister and I somehow got a whole boatload of various things, like IBS, random allergies to metal, a lifelong inability to sweat, and a predisposition to develop hypothyroidism. Not sure if that last one applies to her, but I have a bad feeling it will. Our paternal grandmother had some similar issues. So whatever it is it's pretty strong, I hope her son didn't inherit it. I'm glad there's a treatment for you, I hope it keeps you alive and healthy for a good long time. I know immunosuppressants can be dangerous if you get an infection, so I wish you the best of luck. Ours aren't as bad as yours so far, which is good because as far as I know there's no real treatment for us.
@Amber Kat HI Amber,
I have been very surprised by the comment section from this thread, it's been over a year since this was originally posted and it's still being commented on. Sifi had a good piece but it was geared more toward females, I just wanted to comment that the guys are out here too living the dream. Sine this post I have lost the ability to speak coherent sentences, I know what I want to say and can communicate ok but due to my immune system attacking the Mylan sheath around my nerves I have been left with a number of tics that I can't hide anymore. I am looking at the posability of MS now along with dealing with MMP. I go in next month for a 2 1/2 hour MRI that they are knocking me out for. It's the next step.
I guess the long and the short of it is, your right, they don't know. But by poking and proding us it may make things better for our children and future generations dealing with immune system disorders. Maybe make them a thing of the past. Thank God for good health insurance.
God bless you and your family.
This is 1 of the only channels that can ask a question, not really give a definitive answer , and I'm ok with it. Lol
being a woman and having autoimmune hepatitis I feel this deeply
Was scrolling awhile to find this comment. Team Hep, represent.
wow, this is one of the most interesting SciShow videos i've seen in a while, great work.
Hank, thank you so much for talking about this topic, it’s so important. You got a subscriber out of me.
MS runs in my family though the claim it isn't genetic. Aunts, cousins and even my in laws. During pregnancy the symptoms have virtually disappeared for multiple women in my family and the symptoms return almost right after giving birth. While hormones may not be the cause, they are likely the best way to mitigate and manage MS if not other autoimmune disorders.
I've been checked for MS since it also runs in my family. My doctor said that you're more likely to get it if a family member has it. That seems hereditary to me.
What's very interesting 😮 maybe it has something to do with the high levels of progesterone that's being produced during a pregnancy 🤔
My asthma has disappeared post menopause. It also vanished during each prgnancy. Hardly affected by allergies,now,too! Bliss ! I'm so curious why, & really want explanations!
UCLA is doing a clinical study
This was one of the most fascinating sci show videos I've seen in a while! Thanks for covering this! I have vitiligo, which is considered an autoimmune disease. I've been told that my chances of getting another autoimmune disease (like rheumatoid arthritis or a thyroid disorder) are higher. I've been lowkey paranoid about the arthritis especially because if I lost the ability to knit, I think I'd lose the will to live. I had apl leukemia when I was 29 yrs old (now in remission) and since I had to have a bone marrow biopsy sent off to see if I was in remission on a chromosomal level, they also noticed a extra copy of RUNX-1 on about 10% of my cells- something that "suggests trisomy 8". I didn't have any physical or developmental abnormalities (aside from apparently not talking at as early an age as most children do, according to my mom). I wish I'd gone into immunology or a field studying genetics - this is all very interesting to me!
Even if you get RA, you can still knit! I was diagnosed with RA 2 years ago, and I can still knit. I may not be able to knit for as long, but I'm just happy I can still enjoy my hobbies. Hopefully you never get it, it isn't fun
You have a lower risk of skin cancer — possibly because you already had a little bit of skin cancer that was caught in time. We don’t know if that is why people have vitiligo but we do know that their skin cancer risk is lower.
@Peter Lund interesting! I just looked that up - I'd never heard about my risk for skin cancer perhaps being less. My oncologist told me that I have an increased risk for blood cancer again in general because I've already had leukemia. I don't believe I've ever had SKIN cancer though before. I'm a little confused by that part of your comment. What do you mean by "you already had a little bit of skin cancer that was caught in time"?
@Peter Lund ah nevermind. I think I understand your comment now. You're saying I may have already had skin cancer that my "over active" immune system caught before I knew it?
Sarah Graham yes.
Immune systems @ my cells: ONE OF THESE THINGS IS NOT LIKE THE OTHERS
Team Lupus here! Who else catches on fire when they go in the sun?
Me, while trying to explain to white people yes, black people do in fact get sunburn...especially when we have Lupus.
@Billie Alexander Itchy ouchie solidarity & death to the day star!
There's also so little information on what melanated folks should be looking for with sunburn because it presents differently in darker skin as do cancers. I've literally only seen one post out of hundreds about sun safety (which in general, is a very good thing to be talking about) actually talk about dark skin sunburn and show examples, because it's always from a light skinned angle and most information only just says "yes, you should wear sunscreen even if you have dark skin" (again, a good thing, but not always helpful).
(I should note that I am a beauty creator, so I follow a lot of beauty/science people, and now, I'm actually seeing loads of Black beauty/skincare creators constantly talk about sun protection and there are Black-owned sunscreen brands popping up too!)
@Lorenyth LOL!
this channel is too good. pls don't go anywhere SciShow, we love you
Oh god he said sitting on the couch shoveling in Doritos....how did he know?
This video is comically sciency ^^' Summary: "It's all one huge complex mess and we have no clue whats going on".
SciShow - 2020-01-29
This video was sponsored by Fasthosts. Fasthosts are giving UK viewers the chance to win tickets, flight, and accommodation to SXSW 2020 by answering my Techie Test question: https://www.fasthosts.co.uk/scishow
Grace Gaskell - 2020-05-04
@alexander Wiggin
Uh-huh, now you know how I (someone who's live my whole life in the U.K.) feel when I see 'do thing * for a chance to win * other thing IF you live in the u.s.'
It's SSOO rare to see things like this that even apply outside the u.s, yet alone apply exclusively to a country that isn't america.
You have no idea how refreshing it was to see this!!!
alexander Wiggin - 2020-05-04
@Grace Gaskell well sorry for sounding ungrateful, I didn't even know things like that were rare in the UK.
Grace Gaskell - 2020-05-04
@alexander Wiggin
Didn't mean to imply you sounded ungrateful.
About whether it's rare or not...
I don't think it's rare for things like 'fasthosts' to exist, it's more that it's rare to see them being represented on the internet like this.
(Although if you're talking about give-aways, then yes, it is extremely rare that a give-away will apply to non-u.s. countries - if it does, it's almost always just Canada.)
WraithlingRavenchild - 2020-07-16
How about them tickets to sxsw 2020? Hear it is going to be to die for this year.
NecrochildK - 2021-05-16
As a trans man, I can say in regards to pain, testosterone reduces pain a noticeable amount.