NurdRage - 2017-08-26
In this video we get Guanidine Carbonate and Hydrochloride from no-lye hair relaxants Related videos: Aspirator vacuum pump: https://www.youtube.com/watch?v=tYLlkTDstmo Donate to NurdRage! Through Patreon (preferred): https://www.patreon.com/NurdRage Through Bitcoin: 1NurdRAge7PNR4ULrbrpcYvc9RC4LDp9pS Glassware generously provided by http://www.alchemylabsupply.com/ Use the discount code "nurdrage" for a 5% discount. Social media links: Twitter: https://twitter.com/NurdRage Facebook: https://www.facebook.com/NurdRageYoutube/ Instagram: https://www.instagram.com/nurdrageyoutube/
"Botanicals".
Give me a break.
lol, and the primary ingredient is guanidine... which is made industrially by completely artificial means.
How much did the box set you back?
I found it on Amazon, looks likes it's about $20 bucks (free shipping) in the US, and $10 plus $25 shipping in Canada. Why the pricing is so weird in Canada I don't know. (And it's not even crossing the border - shipped from Ontario)
I see you've discovered the Canuck tax. In addition to GST.
Oh my God, I didn't know chemistry could be so tense! This is so exiting! Is it gonna work? Is it not gonna work? I can't tell! This is better than Game of Thrones!
Needs more incest and betrayal tbh
Ghost2Coast wtf
NR bringing you chemistry one video at a time now comes with occasional unboxing therapy
Nice find. Albeit expensive as you mentioned. If you fancy a bit of danger you could do what I did on my channel and heat NH4NO3 and urea to form guanidine nitrate in good yield which could easily be converted to the carbonate and finally the chloride. Downside is you need to heat an explosive substance for several hours.
The sludge is Denatonium HCl salt. You had Denatonium Benzoate and converted to Den.HCl and benzoic acid. Checking the vapour-pressure nomograph I suspect you have the benzoic acid mixed in, unless guanidinum benzoate precipitated as well.
@juanisabastard sometime you just don't learn about it, it just comes
I was about to leave the house... have to watch this first... priorities
What 2 videos at once... *checks calendar*... its not Christmas yet!
Copyrighted material is fine, patent inventions are different. Copyright protects your work of art (any form) from being sold. Patent provide exclusive monopolies for manufacturing and distribution for the life of the patent in exchange for the disclosure. Both are finite, but patents extend further. I'm not sure of the reasoning, but that is the law here in Canada. So yes he is infringing Canadian patent laws so long as the compound is protected, which I am unsure of.
I'm not sure where you get your information from. But the laws are pretty clear in stating the exclusive monopoly of a patent extends to this instance. Please read this section on the Canadian patent website. http://www.ic.gc.ca/eic/site/cipointernet-internetopic.nsf/eng/wr03586.html
This is a direct quote from the Canadian patent website "When you have exclusive rights to an innovation, you have an effective way to stop others from making, using, selling or importing your product or process" It does not differentiate between manufacturing and manufacturing for sale. Both sale and manufacture are prohibited. You can't make it, and if you buy it you cannot resell it. That is what this means.
Andre Grundy thanks for clearing that up, Though i guess even if they were to take NerdRages compound from him, he would still be able to upload the videos.
Nevertheless, as i recall an Australian school in there chemistry lab synthesized the compound, im not sure if this is just slight differences between countries and there patent laws, though this might suggest that it is unlikely for the patent holders of this compound to bother engaging in any kinda legal action.
It would be rather pointless anyway and serve only to demonize the patent holders, this is after all merely for education purposes.
No problem, I'm happy to help! And that is the glory of youtube! It will be very tough to legally prove he made this compound. As for the Australian school, I did read about that and thought the same thing. I cannot speak for Australia but in Canada, researchers at universities can access and use patented material only for research. Their research if published, cannot be patented unless they pay the licensing fee or are otherwise authorised to by the patent holder. For example, you synthesise a drug and their intermediates and all of them are patent protected. I can make the drug and conduct experiments (animal trials, use it as a precursor etc) with it so long as I do not use the results for financial gain and only if I am working for a university. Patents are wonderful in the sense they give you great power over your intellectual property, but that power can be abused and is why he made this series!
Considering only the successful reactions, what's is the overall cost of your synthesis? let's say normalized by mass, for example per gram. can you tell it to us at the end of this serie?
You can probably shave off costs on almost every step so an estimate of the first route is kinda pointless.
Thank you for the reply. keep up the great work!
each step is only about $50-$100,
But it's the fact that I personally failed so much before i got them right that some steps cost +$1000 with the number of repeats and do-overs i had to do. But now that i've shown how to do them. Anyone copying me shouldn't have spend that much.
Despite my many successful ATX PSU conversions (primarily for electrochemistry), there were many more failed attempts. For example, a single wrong move of my hand resulted in a fried PSU and a tripped circuit breaker due to a AC/DC short. Then I spent a week looking for another scrap PSU, buying radio parts and redoing all the soldering and rewiring. Failures are expensive. And I think that the software field is not an exception.
But once you move beyond the individual script scale and start overseeing the whole chain of developing a software product, especially for commercial purposes, it is still subjected to human fallibility. Bugs, glitches, release delays do not occur by themselves.
Utility program and game developing industries are huge and seemingly insignificant mistakes such as a typo or spaghetti code can cost millions in the long run.
Science is a business, just like any other. You can't just run experiments and collect results for the sake of it. Managing your time and resources, staying afloat, attracting funding, expanding, modernizing - it forces you to see the big picture.
Next video will likely be a filler video on sulfuric acid concentration. Not sure when i'll get to step 6 of pyrimethamine but hopefully very soon.
NurdRage have you tried lead dioxide electrodes from lead ingot yet??
Can't wait!
Good luck on making pyrimethamine.
"the solution has been stirred for 2 weeks ..... yes i've been on vacation, why?" -eyeballing :D
How do you know youve isolated a chemical when you have somewhat unknown inputs like this? Like that slime- how do you know youve eliminated all the other classes of chemicals?
Also great work! Really picking up again on the pyramethamine!
Yeah I'd like to know that as well, I'm curious if it's just more eyeballing lol
i don't. but i consider what contamination remains acceptable for what i want to use it for.
NurdRage no substitute for smarts!
He has sent some chemicals to a lab for "Nuclear magnetic resonance spectroscopy" to check what he had a few times before and he might do it with the final product as well.
well absolutely for the final product!
He may not need to for an intermediate step, though if he has problems he may want to revisit this synthesis and purity.
Is it just me or does melting your hair and then resolidifying it sound really bad for said hair?
NurdRage, now with unboxings of hair products ;)
I'm so excited that you're almost there!
I hope you have a plan for some other projects to take on after this one is finished. Your videos are so interesting to watch I'm always waiting for the next one ^^
Amazing what junk people put in their hair... :P
Love your videos, thank you a lot for making your videos :D
Exciting times ! Step-by-step molecule assembly - in a garage ! Awesome.
After watching Primitive Technology's latest video, I started wondering if someone like you would be able to produce a photosensitive liquid from scratch (without buying anything) to reinvent photography. Let's just assume that you have the necessary laboratory glass and readily available metals like silver and copper in a mine and river. Would you be able to produce silver nitrate or even better, halides?
It's a lot of mining, but it's possible. Just get some saltpeter and sulfuric acid, mix it and shield your eyes, and then chuck the silver on it
You can buy a lot of amazing chemicals in drug stores or just basic shops, you just need to extract them
Can you replicate a flameless ration heater?
sounds like a good idea, i'll consider it.
Ha ha ha ! Hardcore determination :')
Haha this a step towards Guanidine lO4? ;)
and my mom used to use this to straighten my hair as a child....
so much hype for the end of this series
Almost there ! Happy to see you have not given up on the pyrimethamine synthesis.
Had you considered urea+P2O5? It seems so obvious but I can't find a report of a recent attempt. Hair relaxant an unlikely purchase round here.
let me know of a domestic source of P2O5 and i'll give it a try.
Maybe, urea phosphate is already half-way? I heated 40g urea with 25g of ancestral pentoxide and it frothed, even too nicely. I wasn't however able to get it to fuse after this. I presume the very white chalky substance is urea phosphate. It doesn't visibly react with water and I'm wondering what to do next.
I have asked Chem Player. Maybe they have an idea?
That's a way you could incorporate product placements into your videos lol
I wish. but no i didn't get paid at all.
Hey NurdRage. I have a question, what is more hygroscopic, sodium nitrate or ammonium nitrate?
At first I thought he was going to make Guanidine Nitrate!
What would you use pyrimethamine for anyway?
nothing really, it's just a challenge, like climbing mount Everest.
What is your next plan nurdage! I suggest you make potassium perchlorate
In commercial practice, the relatively strong organic chemical base, guanidine is usually present in the form of guanidine hydroxide. However, guanidine hydroxide is not generally stable for long periods in aqueous solutions. Consequently, it must be prepared fresh just before using.
Guanidine hydroxide is generally prepared by reacting an inorganic chemical base such as an alkaline earth hydroxide with an aqueous solution of a salt of guanidine, where the anion of this guanidine salt forms a precipitate with the cation of the alkaline earth hydroxide. In commercially available products of this type, the guanidine hydroxide is generally prepared using guanidine carbonate and calcium hydroxide.
What do you think about "urea hydrochloride" ??
Maybe slightly expensive, than production classic guanidine nitrate, but much beautiful all this reactions in this video. And more safely. And in chemistry should by the beauty. Must be beauty.
Laboratory of Liptakov Then you must enjoy working with all of those ammine complexes, so many great colors!
So, what's the chance you'll try to totally synthesize folinic acid since that's the other half of the complex that makes up Daraprim?
Anyone know a good book that goes over how to make all basic chemicals?
....kind of like the Merck Index, or is that my best bet
eyeballing and intuition often gets you closer to your product than calculating
I will not comment on what does this slime @3:46 look like...:D
And why do you want this chemical in your lab? What can I do with it? Is it psychoactive?
Am I the only one seeing this video a bit choppy?
With any research you have to start somewhere. Eyeballing is really an educated guess. Intuition based on years of experience isn't a bad starting point. Then through experimentation, you refine the recipe.
Thanks for another interesting video.
You should have just picked it up as nitrate and converted it. https://www.pyrochemsource.com/Guanidine-Nitrate-GUANIDINE-NITRATE.htm
I'm late!
Maybe check out AllChemystery's methods for making guanidine bicarbonate and guanidine nitrate.
Hi😊
A lot of different oils and extracts from plants.
ALMOST THERE!?!?!?!
Isnt Guanidine component of DNA?
No, that's guanine.
misoup1
However you can get guanidine from the decomposition of guanine
SigEpBlue - 2017-08-26
It's simultaneously terrifying and reassuring that chemical and electrical engineering use the 'eyeball' method. Fairly certain mechanicals use it, too. lol