> chemistry > divers-organiques > cyclisations > knorr-pyrrole-synthesis-of-knorr-s-pyrrole-corrosive-chemistry

Knorr Pyrrole Synthesis of Knorr's Pyrrole

Corrosive Chemistry - 2020-10-06

In this video I show the Knorr pyrrole synthesis of 3,5-diethoxycarbonyl-2,4-dimethylpyrrole, also known as diethyl 3,5-dimethylpyrrole-2,4-dicarboxylate, also known as simply Knorr's pyrrole. 
This is a nice one pot reaction with 32.5g of ethyl acetoacetate, 75mL of glacial acetic acid, 8.7g of NaNO2, and 16.7g of zinc.


https://www.patreon.com/corrosion

h68 - 2020-10-06

Fantastically done!

Sebastian - 2020-10-19

Your videos are one of the best i've seen in a while, the music, the chemistry, the aesthetic, I love them all! Please never stop uploading!

R Johnson - 2020-10-07

Your channel is outstanding, dude!
A small suggestion:
Because of the fact that some chem-related channels disappear, I use a program to save every video automatically.
The only drawback to this system is that it doesn't automatically save the video description.
If you post links to (for example) research papers in the description, if that video disappears, those references do too.
If you could just flash the link, in text, at the end of the video, that would mean the reference can still be found even if the video disappears.

But again, thank you so very much for taking time & resources to make these unique videos!

Ad Hominem - 2020-10-07

Just lovely Corrosive. Love the aesthetic as well; keep it up

Lab Lulz - 2020-10-16

Nice work, I like the insulated recrystallization chamber - I often use a large hot water bath for thermal inertia. The intermediate green when the zinc is added is cool too

Ben zen - 2020-12-28

which vacuum pump do you use?

Kevin Bauer - 2020-10-09

Nice lab technique! I liked the low-key music in the background as well.

Chem X - 2021-05-23

another great video

MysteriusBhoice - 2020-10-07

so I bet this isnt the same stuff used in Knorr meaty seasoning XD!!

Narogen - 2020-10-06

Excellent video! (Also, very good music)

qaiser abbas - 2021-10-04

Hydroxy propyl methyl cellolus formula and raw material please share with me

Daniel Cezar - 2020-10-11

nice video! heterocyclic synthesis is very beautifully rare around here comparing to other most common stuff.

But WHY THE HECK is there written 'nile red' into your glassware?

I mean hes got the least valuable channel on chemistry, full of scammer chem, false synthesis (that are more like simple extractions) and gummy bears shit only for receiveing money and views from stupid kids xD

and also the guy isnt even a real chemist (ok thats maybe why he calls "making/synthesizing caffeine" just dumb solvent extracting it from coffe or cocoa or shit like that.

that would be plausible only if you gained that beaker or whatever else you have like that for free!
But even then i would scratch the name off of it xD

Corrosive Chemistry - 2020-10-14

I got my nilered glassware a couple years ago back when he was still doing organic syntheses instead of popsci stuff

Shxnw - 2020-10-07

Let’s collab, Shawn edits x corrosive chemistry 🤯🤯🤯

R Johnson - 2020-10-06

Interesting!
(Also: FIRST to comment!)