> chemistry > amines > making-ammonium-methyl-sulfate-thy-labs

Making Ammonium Methyl Sulfate

Thy Labs - 2022-06-21

In this video we are making ammonium methyl sulfate from sulfamic acid and methanol. This stuff may be used to make methylamine sulfate.

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@dominike8430 - 2022-06-21

I misread the title and was shocked that you were about to synthesize Methylsulfate 💀

@mikegLXIVMM - 2022-06-22

It's great that you show us how to test for the substance.
I don't have access to any expensive equipment like spectrometers and qualitative tests can be a hassle a lot of times.

@THYZOID - 2022-06-22

It isn’t a great test but at least it shows the presence of said substance

@Ambient_Scenes - 2024-07-06

This is really cool! Thank you for making this video.

@Kall1208E - 2022-06-21

You can test for methylamine sulfate by performing a reductive animation of your favourite ketone xD

@THYZOID - 2022-06-21

No

@Kall1208E - 2022-06-21

@@THYZOID good

@Randomguy82934 - 2025-07-06

you need to basify it first

@midwestchem368 - 2022-06-21

I forgot to mention of discord ive done this reaction and actually tried a second time with ethanol instead and I still need to attempt to do the rearrangement but im hoping ethylamine can be produced this way. If so that could mean a few different primary amines could theoretically be produced starting from Sulfamic acid. By the way when I boiled it to dryness the molten ammonium methylsulfate once it started to solidify must have been exothermic because more methanol boiled off really vigorously. Just a strange side note.

@THYZOID - 2022-06-21

Ethylamine can not prepared using this route iirc

@dandan-gf4jk - 2022-06-21

@@THYZOID :(, btw can you make a video on triethanOL amine synth? It's quite useful as a complexing agent but idk if it's doable in home lab

@THYZOID - 2022-06-22

@@dandan-gf4jk Na man I can’t do that. That’s some industrial grade chemistry

@SodiumInteresting - 2025-01-05

Love that filtration flask

@FullModernAlchemist - 2022-06-23

Awesome video!

@aupluck9328 - 2022-06-21

very beautyfull

@jozefnovak7750 - 2022-09-29

Super! Thank you very much!

@chemistryofquestionablequa6252 - 2022-06-21

Awesome!

@ThatChemistOld - 2022-06-21

interesting!

@magnuswootton6181 - 2024-02-21

love ur vids!!

@JustinKoenigSilica - 2022-06-21

Methylamine 😳

@THYZOID - 2022-06-21

Here you could even buy methylamine HCl by the kilo legally

@1HeartCell - 2022-06-21

I was always bugged by how they had to steal it in that famous series everyone knows. Just make it yourself if youre such a good chemist

@Aikku93 - 2022-06-21

@@1HeartCell I'm pretty sure the DEA "encouraged" the producers to switch around all instances of MeNH2 and a certain phenylated carboxylic acid (or its methyl ketone) for whatever reason. Then some things make more sense; for example, they'd have to steal said acid/ketone instead of MeNH2 (since it would be a more controlled substance), as well as the cartel chemist would've been upset that Jesse didn't know how to synthesize MeNH2 rather than PAA (which is actually a much more sensible reason for getting upset).

@dimaminiailo3723 - 2022-06-21

@@THYZOID What did you do this preparation for? I know only the rearrangement to MeNH2 ;/

@THYZOID - 2022-06-22

@@dimaminiailo3723 And that’s my main plan

@bobsagely812 - 2022-06-21

Would this work for ethylamine and propylamine too?

@THYZOID - 2022-06-21

Apparently it doesn’t work for ethylamine

@SuperAngelofglory - 2022-06-21

ChemPlayer had a video about making CH3NH2 from CH3NH4SO4, but I think this is the first time I see the synthesis of the salt. Btw, is it a strong alkylating agent?

@JoeyVX - 2022-06-21

He also made a video on how to make this product as step 1. Too bad his videos were taken down..

@THYZOID - 2022-06-21

Idk if it is a strong alkylating agent but I doubt it as it isn’t really toxic. Most alkylating agents are toxic.

@deckekuschel3615 - 2022-06-21

Only at higher temperatures, it would be possible to make nitromethane with it.

@deckekuschel3615 - 2022-06-21

@Experimental Chemistry i said it would be possible, not it is legal

@deckekuschel3615 - 2022-06-21

@Experimental Chemistry xD

@chanheosican6636 - 2022-06-22

Interesting I have these chemicals but I am afraid to try this. What would be it use?

@THYZOID - 2022-06-22

Methylamine gas for my liquified gasses collection in ampoules and making metal complexes.

@chanheosican6636 - 2022-06-22

@@THYZOID Metal complexes that sound cool!

@bromisovalum8417 - 2025-04-03

4 hours of reflux "a very long time"? kek, a long time for me is more like 40 hours reflux, like required for acidic hydrolysis of tertiary amides

@THYZOID - 2025-04-03

my longest one was an entire week lol