Hazel Chem - 2016-08-02
Synthesis of the nitrotoluene isomeres by direct nitration. Today we are synthesizing nitrotoluene and seperate the single isomeres. The paraproduct is used for the synthesis of benzocaine over PABA. I used: - 80ml toluene - 75ml nitric acid 65% - 95ml sulfuric acid 98%
Btw - i did this synth over the weekend. Used your video as a guide (along with chemplayers). Very helpful - so thanks!
would be informative WITHOUT crap music at 100 dB
The chanel is going well & brave. Keep going on the alt. platforms and pay no attention to ignorance.
QUESTION.........I see on your list of upcoming videos you are going to do sodium ethyl sulfate. Will you make it anhydrous of ethanol?????????? Like i recrystallized mine from ethanol and the crystals were PERFECT. But doing it that way i really made sodium ethyl sulfate mono ethanol hydrate. Well not sure if it is called a hydrate since the liquid hydrating the salt is ethanol and not water but i am sure you get what i am saying. Will you make the mono ethanol hydrate of sodium ethyl sulfate or PURE sodium ethyl sulfate?????????? I know the temp it needs to be at to dehydrate and what temp the sodium ethyl sulfate decomposes so i know how to do it on paper but i never did it in real life. Was going to heat it under a vacuum to get the dry "NO ETHAOL" sodium ethyl sulfate but it took so long to make the stuff i was like screw it. Let the EtOH just be incorporated in the crystalline lattice .....screw it
Holey headphones warning batman!
How hot did you let the nitration get?
Yield?
GREAT VIDEO............It is funny how the predicted "literature" yields show ZERO effects of steric hinderance at the ortho positions. A methyl group must not be that big of a deal on a benzene ring when it comes to steric interference. There was actually more coupling to the ortho positions with each getting 32.5% and the para position only getting a 30% yield predicted by literature. I wander if the literature is SLIGHLY wrong on their predicted yields?
Nitrotoluenes smell like bitter almonds
QUESTION: I sometimes think of what other nucleophiles besides benzene. can react with a positive nitronium ion but can never think of one. I always have 2 problems. One is that the neucleophile can not take acid or water in the experiment. Like reacting nitronium ions with a grignard reagent like ethyl magnesium bromide. Two is the nitronium ion would add to an oxygen and make an ester instead of a nitrate. Like reacting it with the double bond of a carbonyl. The carbonyl carbon would be delta positive so the positive nitronium ion would have to add to the oxygen on the double bond....i am guessing. Also nitronium ions would add to an alcohol to make an ester. IS THIS REALLY THE ONLY REACTION A NITRONIUM ION CAN HAVE AND MAKE A NITRO GROUP INSTEAD OF AN ESTER?????????????????????????????????????????????????????????
good video, nice job.....but are you italian?
on the vessels all the words are german, so i guess no.
its a reupload yt took it down on the channel of the oreginal creator
Nice. Let's make the indole from o-nitrotoluene and diethyloxalate.
Really like your videos! but I have a few questions...
Why don't you pour the reaction mixture in ice water, filter it of an wash it 2/3 time with carbonate solution on the frit? Would have save you a lot of time and fiddly work with the separatory funnel. Also, precipitates tend to clog the stopcock. Thats why your way is kind of unusual :D
What background do you have? Are you a lab technician trainee or are you simply interested in chemistry and teach yourself?
your idea could work if your ice bath is cool enought but i think you´ll have a lot of lost do to p-produkt thats still disolved in the o-m mixture.
to the background: I´m still in school and teaching me the stuff myself butt channels like ChemPlayer (RIP :/ ) Nile Red and so on are my inspiration
mfg HazelChem
Plz avbel
Is this the same as O toluidine?
nope toluidine has an aditional NH2 group
mfg hazelChem
Toluidine is made from the nitrotoluene through a reduction with iron/acid.
@Txazi 238 with steel nails and acetic acid.
@psycronizer you may to try)
TNT
the dynamite ^^ yeaaayyyy tnt
Bernd Jendrissek - 2019-01-10
Narration sound level: 2.4 Filler music sound level: 8 bazillion
Hazel Chem - 2019-01-19
well thats right but in my current videos... at least i hope so it is better :D
mfg hazelChem